Liver Cancer Cases to Double by 2050—But 60% Are Preventable

A new global study warns that liver cancer cases will nearly double by 2050, rising from 870,000 in 2022 to 1.52 million annually. Despite being the third deadliest cancer, experts say three out of five cases are preventable.

Key Risk Factors

The surge is attributed to:

• Obesity-related liver disease (MASLD), formerly known as fatty liver disease
• Alcohol consumption, projected to cause 21% of liver cancers by 20504
• Viral hepatitis, especially hepatitis B and C, which remain leading causes

Prevention Is Possible

The Lancet Commission urges global action:

• Vaccination at birth for hepatitis B, especially in low-income regions
• Public awareness campaigns targeting obesity and alcohol risks
• Routine liver screening for high-risk groups, including diabetics and obese individuals

Expert Insights

Professor Jian Zhou of Fudan University emphasized that liver cancer is “one of the most challenging cancers to treat,” with five-year survival rates as low as 5%. Yet, with early detection and lifestyle changes, many cases can be avoided.